Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.32 |
| ▸ | ESR1 | P03372 | 5/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349568 | 0.86 | ABL1 (0.41) | ABL1 | |
| SCHEMBL31349532 | 0.80 | ABL1 (0.41) | ABL1SLC5A1 | |
| SCHEMBL31349450 | 0.78 | ABL1 (0.36) | ABL1 | |
| SCHEMBL31436512 | 0.78 | ESR2 (0.30) | ESR2 | |
| SCHEMBL25316223 | 0.75 | AR (0.42) | ABL1 | |
| SCHEMBL26023696 | 0.75 | AR (0.42) | ABL1 | |
| SCHEMBL30507171 | 0.75 | AR (0.42) | ABL1 | |
| SCHEMBL31349584 | 0.74 | MAP3K12 (0.36) | ESR2ESR1 | |
| SCHEMBL31349496 | 0.73 | HCAR1 (0.39) | ABL1 | |
| SCHEMBL31698068 | 0.65 | ABL1 (0.37) | ABL1ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743078-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015104-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |