Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349528 | 0.86 | ABL1 (0.42) | ABL1 | |
| SCHEMBL31349532 | 0.82 | ABL1 (0.41) | ABL1 | |
| SCHEMBL31349450 | 0.78 | ABL1 (0.36) | ABL1 | |
| SCHEMBL31698362 | 0.78 | ABL1 (0.37) | ABL1HCAR1 | |
| SCHEMBL31349425 | 0.78 | HCAR1 (0.33) | HCAR1 | |
| SCHEMBL31698694 | 0.77 | ABL1 (0.36) | ABL1HCAR1 | |
| SCHEMBL31698880 | 0.76 | PIK3CD (0.35) | ABL1HCAR1 | |
| SCHEMBL31349589 | 0.75 | MAP3K12 (0.36) | HCAR1 | |
| SCHEMBL25319241 | 0.74 | AR (0.39) | HCAR1 | |
| SCHEMBL30507492 | 0.74 | AR (0.39) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743078-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015104-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |