SCHEMBL31349608

SCHEMBL31349608

Cn1c(C2CC(C)(O)C2)nc2cc(OCCN3CCC4(CC3)C(=O)Nc3ccc(C(F)F)nc34)cc(C(F)(F)F)c21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ADCY10 Q96PN6 1/20 0.31
▸ DRD2 P14416 2/20 0.30
▸ TNK2 Q07912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31349561 0.90 DRD2 (0.30) DRD2
SCHEMBL31349440 0.88 DRD2 (0.30) DRD2
SCHEMBL31436434 0.86 DRD2 (0.36) DRD2
SCHEMBL31349508 0.86 — —
SCHEMBL31349476 0.86 DRD2 (0.30) DRD2
SCHEMBL31349501 0.85 DRD2 (0.31) ADCY10DRD2
SCHEMBL31349549 0.84 — —
SCHEMBL31349567 0.84 — —
SCHEMBL31349635 0.84 ADCY10 (0.30) ADCY10
SCHEMBL31349594 0.82 DRD2 (0.30) ADCY10DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743078-A2 APOL1 INHIBITORS AND METHODS OF USE Maze Therapeutics, Inc. (US) 2026-05-20 — — EP disclosed
WO-2025015104-A2 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS, INC. (US) 2025-01-16 — — WO disclosed
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