Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.81 |
| ▸ | HPGD | P15428 | 10/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Jatamansin SCHEMBL29385603 | 0.90 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| Jatamansin SCHEMBL12062120 | 0.90 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| Jatamansin SCHEMBL26671050 | 0.90 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| Jatamansin SCHEMBL14523891 | 0.90 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| Jatamansin SCHEMBL30634819 | 0.90 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL29707867 | 0.89 | KDM4E (0.76) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL15444380 | 0.82 | KDM4E (0.57) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| (+)-Lomatin SCHEMBL29707947 | 0.82 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| Lomatin SCHEMBL6273711 | 0.82 | KDM4E (1.00) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL4740846 | 0.78 | MAOA (0.79) | KDM4EHPGDCYP3A4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119124764-A | Preparation method and quality detection method of high-purity Hyuganin D | 江苏省中医院 | 2024-12-13 | — | — | CN | disclosed |