Jatamansin

Jatamansin

SCHEMBL12062120

C/C=C(/C)C(=O)O[C@@H]1Cc2c(ccc3ccc(=O)oc23)OC1(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 15/20 1.00
▸ HPGD P15428 12/20 1.00
▸ CYP3A4 P08684 3/20 1.00
▸ HSD17B10 Q99714 3/20 1.00
▸ ALDH1A1 P00352 13/20 0.62
▸ MAPT P10636 3/20 0.62
▸ HTT P42858 3/20 0.61
▸ LMNA P02545 2/20 0.61
▸ MEN1 O00255 2/20 0.61
▸ KMT2A Q03164 2/20 0.61
▸ RCE1 Q9Y256 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ RECQL P46063 1/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ ABCB1 P08183 1/20 0.61
▸ TP53 P04637 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ GAA P10253 2/20 0.60
▸ NPY1R P25929 1/20 0.49
▸ NPY2R P49146 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Jatamansin SCHEMBL26671050 1.00 KDM4E (1.00) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Jatamansin SCHEMBL29385603 1.00 KDM4E (1.00) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Jatamansin SCHEMBL14523891 1.00 KDM4E (1.00) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Jatamansin SCHEMBL30634819 1.00 KDM4E (1.00) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
SCHEMBL31349688 0.90 KDM4E (0.81) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
SCHEMBL29707867 0.86 KDM4E (0.76) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Decursinol Angelate SCHEMBL14310264 0.79 MAOA (0.76) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Decursinol Angelate SCHEMBL3901157 0.79 MAOA (0.76) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Decursinol Angelate SCHEMBL4740622 0.79 MAOA (0.76) KDM4EHPGDCYP3A4HSD17B10ALDH1A1
Decursinol Angelate SCHEMBL3901154 0.79 MAOA (0.76) KDM4EHPGDCYP3A4HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240165190-A1 A HERBO-MINERAL METALLIC PHARMACEUTICAL KIT SARDESHMUKH, Sadanand Prabhakar (IN) 2024-05-23 — — US claimed
US-20230338329-A1 CANNABINOID EMULSION COMPOSITION AND METHOD OF MANUFACTURING GORE DOUGLAS (US) 2023-10-26 — — US claimed
EP-4236690-A1 ANTIVIRAL ESSENTIAL OIL COMPOSITIONS Erdogmus, Hüseyin (TR) 2023-09-06 — — EP claimed
WO-2022269576-A1 A NEW DRUG DELIVERY SYSTEM OF EFFERVESCENT PRODUCTS SCITECH SPECIALITIES PRIVATE LIMITED (IN) 2022-12-29 — — WO claimed
US-20220370535-A1 ANTIVIRAL ESSENTIAL OIL COMPOSITIONS ERDOGMUS, HÜSEYIN (TR) 2022-11-24 — — US claimed
WO-2022195415-A1 A HERBO-MINERAL METALLIC PHARMACEUTICAL KIT SARDESHMUKH SADANAND PRABHAKAR (IN) 2022-09-22 — — WO claimed
WO-2022093141-A1 ANTIVIRAL ESSENTIAL OIL COMPOSITIONS ERDOGMUS HUESEYIN (TR) 2022-05-05 — — WO claimed
US-20260117458-A1 METHODS AND SYSTEMS FOR PLASMA COLOURATION AND PIGMENT FIXATION XEFCO PTY LTD (AU) 2026-04-30 — — US disclosed
EP-4136067-B1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR AND COMPANY LTD (IN) 2026-04-15 — — EP disclosed
WO-2026039879-A1 METHOD AND DEVICE FOR COLOURATION OF SUBSTRATES XEFCO PTY LTD (AU) 2026-02-26 — — WO disclosed
US-12545852-B2 Odorants and compositions comprising odorants S H KELKAR AND COMPANY LIMITED (IN) 2026-02-10 — — US disclosed
EP-3697878-B1 USE OF ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR AND COMPANY LTD (IN) 2026-01-28 — — EP disclosed
US-12522780-B2 Odorants and compositions comprising odorants S H KELKAR AND COMPANY LIMITED (IN) 2026-01-13 — — US disclosed
US-8772252-B2 Coumarin compounds as melanogenesis modifiers and uses thereof NEW YORK UNIVERSITY (US) 2014-07-08 — — US disclosed
US-8563754-B2 Compounds, compositions and methods for preventing skin darkening NEW YORK UNIVERSITY (US) 2013-10-22 — — US disclosed
US-8563754-B2 Compounds, compositions and methods for preventing skin darkening NEW YORK UNIVERSITY (US) 2013-10-22 — — US disclosed
US-20120220545-A1 COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF NEW YORK UNIVERSITY 2012-08-30 — — US disclosed
US-20120220545-A1 COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF NEW YORK UNIVERSITY 2012-08-30 — — US disclosed
US-20110190229-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING NEW YORK UNIVERSITY 2011-08-04 — — US disclosed
US-20110190229-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING NEW YORK UNIVERSITY 2011-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545852-B2 Odorants and compositions comprising odorants ENY2, CDY1; CDY1B, CHRM5 KDM4E 1249/4885HPGD 2292/4885CYP3A4 1747/4885
US-20260117458-A1 METHODS AND SYSTEMS FOR PLASMA COLOURATION AND PIGMENT FIXATION FUCA2, TYR, PRPF8 KDM4E 2494/4885HPGD 3435/4885CYP3A4 225/4885
US-20120220545-A1 COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF TYR, MC1R, MITF KDM4E 79/4885HPGD 2055/4885CYP3A4 573/4885
US-20220370535-A1 ANTIVIRAL ESSENTIAL OIL COMPOSITIONS CYP51A1, NR1H2, CYP2R1 KDM4E 601/4885HPGD 1388/4885CYP3A4 90/4885
US-20110190229-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING TYR, MC1R, MITF KDM4E 274/4885HPGD 574/4885CYP3A4 809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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