Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.52 |
| ▸ | TSPO | P30536 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 18/20 | 0.52 |
| ▸ | HTR2C | P28335 | 17/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350180 | 0.99 | HTR2B (0.53) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350142 | 0.99 | HTR2B (0.53) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350227 | 0.97 | HTR2B (0.51) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350206 | 0.91 | HRH2 (0.57) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350157 | 0.91 | HRH2 (0.56) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350114 | 0.85 | HRH2 (0.44) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350143 | 0.85 | ADORA3 (0.38) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350236 | 0.81 | HTR2B (0.70) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350238 | 0.80 | HTR2B (0.71) | ADORA1ADORA3TSPOHTR2BHTR2C | |
| SCHEMBL31350170 | 0.79 | HRH2 (0.43) | ADORA1ADORA3HTR2BHTR2CHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747254-A1 | <SUP2/>? <SUB2/>?2B?5-HTSEROTONIN RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE THEREOF | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019529-A1 | 5-HT 2B SEROTONIN RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-23 | — | — | WO | disclosed |