SCHEMBL31350347

SCHEMBL31350347

Cc1sc2ccc(OCc3ccccn3)cc2c1C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.54
MAOA P21397 1/20 0.45
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
FGFR4 P22455 1/20 0.41
EDNRA P25101 1/20 0.41
NPC1 O15118 2/20 0.41
MAPK1 P28482 2/20 0.41
RAB9A P51151 2/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
MAPK14 Q16539 3/20 0.40
SMO Q99835 3/20 0.40
PLA2G2A P14555 1/20 0.40
LCK P06239 1/20 0.40
PPARG P37231 1/20 0.40
PDE5A O76074 2/20 0.40
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656221 0.85 PARP10 (0.43) PARP10MAOASMN1; SMN2FGFR4MAPK14
SCHEMBL30656338 0.85 PARP10 (0.43) PARP10MAOAFGFR4EDNRAMAPK14
SCHEMBL30656142 0.85 PARP10 (0.43) PARP10MAOAFGFR4EDNRAMAPK14
SCHEMBL26661097 0.85 PARP10 (0.43) PARP10MAOAFGFR4EDNRAMAPK14
SCHEMBL30655999 0.84 GPR132 (0.43) PARP10MAOAFGFR4MAPK14SMO
SCHEMBL30656047 0.84 GPR132 (0.43) PARP10MAOAFGFR4MAPK14SMO
SCHEMBL31350322 0.83 EDNRA (0.38) PARP10EDNRA
SCHEMBL30655976 0.81 PARP10 (0.40) PARP10MAOAFGFR4MAPK14SMO
SCHEMBL31350375 0.81 ICAM1 (0.41) PARP10EDNRAMAPK1PPARGTSHR
SCHEMBL30656053 0.80 SMO (0.39) PARP10MAOAALDH1A1SMN1; SMN2FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed