SCHEMBL30656221

SCHEMBL30656221

Cc1sc2ccc(OCc3ccccn3)cc2c1C(=O)NC(C)(C)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.43
SMO Q99835 6/20 0.39
MAPK14 Q16539 5/20 0.39
MAOA P21397 1/20 0.39
FGFR4 P22455 1/20 0.39
POLB P06746 1/20 0.38
MDM2 Q00987 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDE5A O76074 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30655951 0.87 EDNRA (0.47) PARP10MAOASMN1; SMN2
SCHEMBL30656034 0.85 SLC26A4 (0.33) PARP10
SCHEMBL31350347 0.85 PARP10 (0.54) PARP10SMOMAPK14MAOAFGFR4
SCHEMBL30656194 0.84 SLC13A5 (0.37) PARP10
SCHEMBL26661097 0.83 PARP10 (0.43) PARP10SMOMAPK14MAOAFGFR4
SCHEMBL30656338 0.83 PARP10 (0.43) PARP10SMOMAPK14MAOAFGFR4
SCHEMBL30656142 0.83 PARP10 (0.43) PARP10SMOMAPK14MAOAFGFR4
SCHEMBL26792937 0.83 PARP10 (0.45) PARP10
SCHEMBL30655957 0.83 CD38 (0.38) MAOASMN1; SMN2
SCHEMBL30656077 0.82 RAB9A (0.35) POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed