Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 5/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574229 | 0.91 | THRA (0.59) | THRATHRBCYP11B1CYP11B2PLA2G10 | |
| SCHEMBL25399834 | 0.91 | THRA (0.59) | THRATHRBCYP11B1CYP11B2PLA2G10 | |
| SCHEMBL31350368 | 0.88 | THRA (0.50) | THRATHRBPDK2 | |
| SCHEMBL31350423 | 0.88 | THRA (0.55) | THRATHRBPDK2PLA2G10PLA2G2A | |
| SCHEMBL31350412 | 0.88 | THRA (0.48) | THRATHRBCYP11B1CYP11B2 | |
| SCHEMBL31350361 | 0.87 | THRA (0.47) | THRATHRBPDK2GLA | |
| SCHEMBL31350394 | 0.86 | THRA (0.48) | THRATHRBPDK2PLA2G10PLA2G2A | |
| SCHEMBL31350370 | 0.86 | THRA (0.46) | THRATHRBPDK2CYP11B1CYP11B2 | |
| SCHEMBL31350387 | 0.84 | THRA (0.48) | THRATHRBPDK2PLA2G10PLA2G2A | |
| SCHEMBL31350392 | 0.84 | THRA (0.52) | THRATHRBPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025019825-A2 | SUBSTITUTED 2-(3,5-DICHLORO-4-(4-HYDROXY-BENZYL)PHENOXY)ACETAMIDE DERIVATIVES | BRII BIOSCIENCES, INC. (US) | 2025-01-23 | — | — | WO | disclosed |