Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.59 |
| ▸ | THRB | P10828 | 14/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399834 | 1.00 | THRA (0.59) | THRATHRBCA12CA1CA2 | |
| SCHEMBL31350403 | 0.91 | THRA (0.49) | THRATHRBPLA2G10PLA2G2ACYP11B1 | |
| SCHEMBL25401057 | 0.89 | THRB (0.61) | THRATHRBPLA2G10PLA2G2A | |
| SCHEMBL30574232 | 0.89 | THRA (0.66) | THRATHRBPLA2G10PLA2G2APTPN1 | |
| SCHEMBL23003630 | 0.89 | THRA (0.66) | THRATHRBPLA2G10PLA2G2APTPN1 | |
| SCHEMBL31350412 | 0.89 | THRA (0.48) | THRATHRBCYP11B1CYP11B2 | |
| SCHEMBL25397334 | 0.88 | THRB (0.62) | THRATHRBPLA2G10PLA2G2A | |
| SCHEMBL25401460 | 0.86 | THRB (0.58) | THRATHRB | |
| SCHEMBL25398618 | 0.86 | THRB (0.60) | THRATHRBPLA2G10PLA2G2A | |
| SCHEMBL25397376 | 0.85 | THRB (0.57) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177667-A1 | THYROID HORMONE RECEPTOR AGONISTS | BRII BIOSCIENCES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |