Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324364 | 0.82 | IRAK4 (0.41) | IRAK4CYP2A6IRAK1MEN1GFER | |
| SCHEMBL31324443 | 0.82 | HTR1D (0.38) | HTR1DKDRMAP4K4TGFBR1IRAK4 | |
| SCHEMBL31324362 | 0.80 | CYP2A6 (0.34) | IRAK4CHEK2BACE1CYP2A6KCNH2 | |
| SCHEMBL31324322 | 0.80 | IRAK4 (0.38) | MAP4K4TGFBR1IRAK4IRAK1KCNH2 | |
| SCHEMBL31351323 | 0.79 | HDAC3 (0.44) | KDRFLT1FLT4 | |
| SCHEMBL31351104 | 0.78 | IRAK4 (0.37) | MAP4K4TGFBR1IRAK4CYP2A6IRAK1 | |
| SCHEMBL31350834 | 0.77 | CHEK2 (0.33) | IRAK4CHEK2MEN1GFERKMT2A | |
| SCHEMBL31351041 | 0.75 | COMT (0.40) | IRAK4IRAK1KCNH2BRAFMAPK3 | |
| SCHEMBL31351306 | 0.75 | HTR1D (0.44) | HTR1DKDRMAP4K4TGFBR1CHEK2 | |
| SCHEMBL5861309 | 0.71 | KDM4E (0.57) | KDRIRAK4IRAK1KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |