Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 3/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324322 | 0.75 | IRAK4 (0.38) | IRAK4IRAK1KCNH2BRAFMAPK3 | |
| SCHEMBL31350907 | 0.75 | HTR1D (0.41) | IRAK4IRAK1KCNH2BRAFMAPK3 | |
| SCHEMBL15438793 | 0.74 | NPC1 (0.46) | BRAF | |
| SCHEMBL5861309 | 0.73 | KDM4E (0.57) | IRAK4IRAK1KCNH2ALDH1A1KDM4E | |
| SCHEMBL31351104 | 0.73 | IRAK4 (0.37) | IRAK4IRAK1KCNH2PIK3CABRAF | |
| SCHEMBL5860842 | 0.71 | KDM4E (0.41) | IRAK4IRAK1KCNH2ALDH1A1NR5A2 | |
| SCHEMBL26785286 | 0.70 | NLRP3 (0.56) | COMTNLRP3BRAFMAPK3MAPK1 | |
| SCHEMBL19461954 | 0.69 | KDM4E (0.54) | IRAK4IRAK1KCNH2BRAFMAPK3 | |
| SCHEMBL31324366 | 0.67 | LGMN (0.37) | IRAK4IRAK1KCNH2PIK3CAMAPK1 | |
| SCHEMBL17678348 | 0.67 | IRAK4 (0.39) | IRAK4IRAK1KCNH2ALDH1A1NR5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |