Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31351045 | 0.83 | IRAK4 (0.36) | IRAK4IRAK1KCNH2TGFBR1MAP4K4 | |
| SCHEMBL31324322 | 0.78 | IRAK4 (0.38) | IRAK4IRAK1KCNH2TGFBR1MAP4K4 | |
| SCHEMBL31350907 | 0.78 | HTR1D (0.41) | IRAK4IRAK1KCNH2TGFBR1MAP4K4 | |
| SCHEMBL31351209 | 0.74 | IRAK4 (0.51) | IRAK4IRAK1KCNH2 | |
| SCHEMBL31351041 | 0.73 | COMT (0.40) | IRAK4IRAK1KCNH2BRAFMAPK3 | |
| SCHEMBL31350797 | 0.72 | IRAK4 (0.47) | IRAK4IRAK1KCNH2MAP4K4PIK3CA | |
| SCHEMBL31351147 | 0.70 | GCGR (0.36) | KCNH2PIK3CAMAPT | |
| SCHEMBL5861309 | 0.69 | KDM4E (0.57) | IRAK4IRAK1KCNH2CYP2D6CNR2 | |
| SCHEMBL5860842 | 0.69 | KDM4E (0.41) | IRAK4IRAK1KCNH2CYP2D6CNR2 | |
| SCHEMBL19461857 | 0.68 | CHEK1 (0.34) | IRAK4IRAK1KCNH2TGFBR1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025003987-A1 | NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 동화약품주식회사 | 2025-01-02 | — | — | WO | disclosed |