Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 12/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28414251 | 1.00 | GSR (0.44) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL4610561 | 0.96 | GSR (0.41) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL27660749 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL4956225 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL21494167 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL3387882 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL17580033 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL21494166 | 0.90 | GSR (0.48) | GSRCPB2DPP4DPP7DPP8 | |
| Lysine SCHEMBL27639977 | 0.89 | GSR (0.47) | GSRDPP4DPP7DPP8DPP9 | |
| Lysine SCHEMBL659927 | 0.89 | GSR (0.47) | GSRDPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340684-A9 | DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6) | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2016-11-24 | — | — | US | disclosed |
| US-20130237429-A1 | DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6) | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130139276-A1 | DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6) | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-05-30 | — | — | US | disclosed |
| US-8309793-B2 | Discovery and utilization of sorghum genes (Ma5/Ma6) | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-11-13 | — | — | US | disclosed |
| US-20100024065-A1 | DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6) | THE TEXAS A&M UNIVERSITY SYSTEM | 2010-01-28 | — | — | US | disclosed |
| WO-2010011680-A2 | DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6) | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2010-01-28 | — | — | WO | disclosed |