Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 4/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855207 | 0.87 | CDC7 (0.38) | TDP2CDC7DBF4CA9CA12 | |
| SCHEMBL22855430 | 0.81 | CDC7 (0.41) | TDP2CDC7DBF4CA9CA12 | |
| SCHEMBL31351723 | 0.80 | CDC7 (0.43) | TDP2CDC7CA9CA12CASP1 | |
| SCHEMBL31351722 | 0.80 | TDP2 (0.40) | TDP2CDC7CA9CA12CASP1 | |
| SCHEMBL31351716 | 0.80 | CDC7 (0.43) | TDP2CDC7CA9CA12CASP1 | |
| SCHEMBL24457369 | 0.80 | PARP10 (0.46) | TDP2MAPTMAPKAPK2PARP1KMT2A | |
| SCHEMBL12077241 | 0.80 | TDP2 (0.46) | TDP2CDC7DBF4CA9ALDH1A1 | |
| SCHEMBL24457584 | 0.76 | PARP10 (0.50) | TDP2CDC7DBF4MAPKAPK2PARP1 | |
| SCHEMBL24457763 | 0.76 | CDC7 (0.33) | CDC7DBF4HSD17B10HPGDPARP1 | |
| SCHEMBL29551627 | 0.76 | CDC7 (0.32) | CDC7DBF4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747244-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | Redx Pharma Limited (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017305-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |
| WO-2025017306-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |