Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574545 | 0.81 | RAB9A (0.48) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL26099158 | 0.80 | ALDH1A1 (0.48) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL31352094 | 0.80 | KDM4C (0.38) | ALDH1A1KDM4ERAB9ANPC1TSHR | |
| SCHEMBL2671293 | 0.79 | CYP3A4 (0.46) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL1406972 | 0.79 | HTT (0.46) | CYP3A4CYP2C19ALDH1A1KDM4EHTT | |
| SCHEMBL25339625 | 0.79 | RAB9A (0.46) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL2672130 | 0.79 | RAB9A (0.46) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL1406913 | 0.79 | RAB9A (0.59) | ALDH1A1KDM4EHTTRAB9ANPC1 | |
| SCHEMBL31352268 | 0.78 | KDM4E (0.45) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A | |
| SCHEMBL29953140 | 0.77 | NPC1 (0.44) | CYP3A4CYP2C19ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002177-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2025-01-02 | — | — | WO | disclosed |