Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273627 | 1.00 | LMNA (0.45) | LMNAPOLBALDH1A1RECQLTDP1 | |
| SCHEMBL26112669 | 0.81 | L3MBTL1 (0.40) | LMNAALDH1A1NPC1SMN1; SMN2DRD4 | |
| SCHEMBL31665009 | 0.80 | HTR2A (0.41) | NPC1HTR2A | |
| SCHEMBL6689898 | 0.79 | DRD4 (0.41) | ALDH1A1RECQLTDP1NPC1KMT2A | |
| SCHEMBL25323979 | 0.79 | CSNK1D (0.43) | — | |
| SCHEMBL26112328 | 0.79 | TSHR (0.45) | LMNAPOLBALDH1A1RECQLTDP1 | |
| SCHEMBL30509476 | 0.77 | HDAC6 (0.36) | LMNANPC1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL15885492 | 0.77 | PDE10A (0.39) | DRD4ATM | |
| SCHEMBL27894720 | 0.77 | POLB (0.45) | LMNAPOLBALDH1A1RECQLTDP1 | |
| SCHEMBL31626515 | 0.76 | LMNA (0.43) | LMNAPOLBALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325471-A | EGFR inhibitors | 缆图药品公司 | 2025-01-17 | — | — | CN | disclosed |