SCHEMBL31353016

SCHEMBL31353016

Cc1ccc(C(=O)C=CC=Cc2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 8/20 0.78
MAPT P10636 9/20 0.68
ALDH1A1 P00352 5/20 0.68
HPGD P15428 3/20 0.68
CYP3A4 P08684 2/20 0.68
RAB9A P51151 3/20 0.62
POLB P06746 2/20 0.62
NPC1 O15118 2/20 0.62
KMT2A Q03164 5/20 0.58
MEN1 O00255 4/20 0.58
HTT P42858 3/20 0.58
NPSR1 Q6W5P4 3/20 0.58
LMNA P02545 3/20 0.58
PKM P14618 2/20 0.58
ATM Q13315 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NLRP1 Q9C000 1/20 0.58
NTSR1 P30989 1/20 0.58
MAOB P27338 6/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31353017 1.00 CYP1B1 (0.78) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL31353024 0.93 MAPT (0.78) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL7193506 0.88 CYP1B1 (1.00) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL77498 0.88 CYP1B1 (1.00) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL1614247 0.88 MAOB (0.74) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL1614248 0.88 MAOB (0.74) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL1614246 0.88 MAOB (0.74) CYP1B1MAPTALDH1A1HPGDCYP3A4
SCHEMBL11470657 0.86 CYP1B1 (0.61) CYP1B1MAPTALDH1A1CYP3A4RAB9A
SCHEMBL11470658 0.86 CYP1B1 (0.61) CYP1B1MAPTALDH1A1CYP3A4RAB9A
Bromide SCHEMBL11319714 0.86 MAOB (0.71) CYP1B1MAPTALDH1A1HPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390715-A Method for catalyzing chiral boron addition reaction of alpha, beta, gamma, delta-unsaturated ketone by nano composite microsphere loaded copper material 湖北工程学院 2025-02-07 CN disclosed