Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.86 |
| ▸ | HPGD | P15428 | 2/20 | 0.86 |
| ▸ | MAOB | P27338 | 7/20 | 0.75 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.75 |
| ▸ | BCHE | P06276 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.75 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.75 |
| ▸ | MAOA | P21397 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193506 | 1.00 | CYP1B1 (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL5753797 | 0.93 | MAPT (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL6200952 | 0.93 | MAPT (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL76030 | 0.93 | MAPT (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| Pentane SCHEMBL28825197 | 0.91 | CYP1B1 (0.82) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| 4,4'-Dimethylchalcone SCHEMBL979560 | 0.90 | MAPT (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| 4,4'-Dimethylchalcone SCHEMBL979559 | 0.90 | MAPT (1.00) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL23789072 | 0.90 | MAPT (0.87) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL10497980 | 0.90 | CYP1B1 (0.81) | CYP1B1MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL11814876 | 0.90 | CYP1B1 (0.81) | CYP1B1MAPTALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233645-A | Method for preparing tri-substituted cyclopentene by MBH/Wittig domino reaction of vinylon insertion | 浙江大学 | 2020-06-05 | — | — | CN | claimed |
| US-6630512-B2 | Antiinflammatory agents; autoimmune disease | BIOGEN, INC. | 2003-10-07 | — | — | US | claimed |
| US-20030018016-A1 | Cell adhesion inhibitors | BIOGEN IDEC MA, INC. | 2003-01-23 | — | — | US | claimed |
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |
| US-6376538-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | BIOGEN, INC. | 2002-04-23 | — | — | US | claimed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | claimed |
| CN-114456086-B | Synthesis method of beta-cyano ketone | 哈尔滨理工大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-118355090-A | Boron-containing cyclic light-emitting compound and color conversion film containing same | 日东电工株式会社 | 2024-07-16 | — | — | CN | disclosed |
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023206835-A1 | CROSS-LINKED NORBORNENE COPOLYMER/CARBON BLACK THREE-DIMENSIONAL NETWORK IMMOBILIZED BIMETALLIC COPPER/GOLD NANO-CATALYST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 湖北工程学院 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023158976-A1 | BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME | NITTO DENKO CORPORATION (JP) | 2023-08-24 | — | — | WO | disclosed |
| EP-1142867-A2 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | MB, MYOC, PDE6A | CYP1B1 4443/4885MAPT 2250/4885ALDH1A1 1091/4885 |
| US-20030018016-A1 | Cell adhesion inhibitors | ICAM1, VCAM1, EPCAM | CYP1B1 3769/4885MAPT 2771/4885ALDH1A1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.