Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31353367 | 0.80 | EPAS1 (0.34) | CA1CA2EPAS1 | |
| SCHEMBL31353319 | 0.79 | GRM2 (0.38) | CA1CA2EPAS1KDM4EALDH1A1 | |
| SCHEMBL32679790 | 0.74 | CA1 (0.34) | CA1CA2EPAS1 | |
| SCHEMBL31353293 | 0.74 | CA1 (0.34) | CA1CA2EPAS1 | |
| SCHEMBL24658986 | 0.70 | LMNA (0.41) | CA1CA2EPAS1MAPTNT5E | |
| SCHEMBL27384778 | 0.69 | EPAS1 (0.32) | CA1CA2EPAS1 | |
| SCHEMBL19782874 | 0.68 | F2RL3 (0.37) | CA1CA2EPAS1 | |
| SCHEMBL31353245 | 0.68 | MAPT (0.35) | KDM4EMEN1ALDH1A1MAPTMPI | |
| SCHEMBL25895920 | 0.68 | PTGFR (0.33) | CA1CA2MEN1ALDH1A1KMT2A | |
| SCHEMBL6410730 | 0.67 | CA1 (0.40) | CA1CA2EPAS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |