SCHEMBL31353293

SCHEMBL31353293

Cc1cc(Br)c2nc(OS(=O)(=O)C(F)(F)F)c(C)nc2c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
EPAS1 Q99814 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679790 1.00 CA1 (0.34) CA1CA2EPAS1
SCHEMBL32679780 0.82 NQO2 (0.42) CA1CA2
SCHEMBL31353158 0.82 NQO2 (0.42) CA1CA2
SCHEMBL19782874 0.78 F2RL3 (0.37) CA1CA2EPAS1
SCHEMBL15383509 0.77 KDM4E (0.42) CA1CA2
SCHEMBL31353367 0.76 EPAS1 (0.34) CA1CA2EPAS1
SCHEMBL31353142 0.74 CA1 (0.33) CA1CA2EPAS1
SCHEMBL9925835 0.72 CA1 (0.35) CA1CA2
SCHEMBL31353319 0.69 GRM2 (0.38) CA1CA2EPAS1
SCHEMBL21191490 0.67 CA1 (0.30) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021217-A1 QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE BEIGENE SWITZERLAND GMBH (CH) 2025-01-30 WO disclosed