Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994257 | 0.76 | MEN1 (0.46) | LMNACA2ALDH1A1MEN1GAA | |
| SCHEMBL13051720 | 0.74 | CYP3A4 (0.40) | LMNACA2ALDH1A1MEN1GAA | |
| SCHEMBL5883309 | 0.74 | ERN1 (0.58) | LMNAPRKDCERN1MAPT | |
| SCHEMBL3851901 | 0.74 | LMNA (0.40) | LMNAPRKDCALDH1A3ERN1ALDH1A1 | |
| SCHEMBL304092 | 0.73 | ERN1 (0.41) | LMNAPRKDCERN1ALDH1A1ALDH3A1 | |
| SCHEMBL12109792 | 0.73 | CYP3A4 (0.34) | LMNAPRKDCCA2ALDH1A1MEN1 | |
| SCHEMBL19503931 | 0.72 | LMNA (0.46) | LMNAPRKDCALDH1A3ERN1CA2 | |
| SCHEMBL6209300 | 0.72 | LMNA (0.46) | LMNAPRKDCALDH1A3ALDH1A1MEN1 | |
| SCHEMBL5254093 | 0.72 | APEX1 (0.45) | CA2MAPTTHRBPTGS2RAB9A | |
| SCHEMBL3185596 | 0.72 | ERN1 (0.50) | LMNAPRKDCERN1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |