Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503931 | 0.84 | LMNA (0.46) | LMNAPRKDCSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2036405 | 0.82 | LMNA (0.39) | LMNAPRKDCSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8459678 | 0.81 | TRPA1 (0.41) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5401095 | 0.80 | ERN1 (0.40) | LMNAPRKDCSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5670692 | 0.80 | TRPA1 (0.38) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5085882 | 0.79 | TRPA1 (0.40) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL27893671 | 0.78 | CDK1 (0.41) | LMNAPRKDCSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2704056 | 0.78 | ALDH1A1 (0.45) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28474799 | 0.77 | CALM1 (0.44) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL21338176 | 0.76 | TDP1 (0.55) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425342-A4 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & CO (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1425342-A2 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | Milliken & Company (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2002077086-A2 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-10-03 | — | — | WO | disclosed |