SCHEMBL32679780

SCHEMBL32679780

Cc1nc2cc(Br)cc(C)c2nc1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.42
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31353158 1.00 NQO2 (0.42) NQO2CA1CA2
SCHEMBL32679790 0.82 CA1 (0.34) CA1CA2
SCHEMBL31353293 0.82 CA1 (0.34) CA1CA2
SCHEMBL4814757 0.72 MEN1 (0.36) CA1CA2
SCHEMBL9925835 0.72 CA1 (0.35) CA1CA2
SCHEMBL15383509 0.71 KDM4E (0.42) NQO2CA1CA2
SCHEMBL25895920 0.69 PTGFR (0.33) CA1CA2
SCHEMBL5973479 0.69 NQO2 (0.56) NQO2
SCHEMBL25896032 0.68 F2 (0.46) CA1CA2
SCHEMBL6139736 0.68 RAB9A (0.40) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586713-A Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases 百济神州(苏州)生物科技有限公司 2026-02-27 CN disclosed