Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26547800 | 0.80 | TDP1 (0.40) | KMT2APDXKKDM4E | |
| SCHEMBL22690074 | 0.80 | SMN1; SMN2 (0.50) | POLBALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL29880065 | 0.80 | ALDH1A1 (0.41) | POLBALDH1A1MAPK1SMN1; SMN2HSD17B10 | |
| SCHEMBL3180693 | 0.80 | NCF1 (0.37) | POLBNR4A2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29374065 | 0.80 | SMN1; SMN2 (0.50) | POLBALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL1710375 | 0.80 | ALDH1A1 (0.41) | POLBALDH1A1MAPK1SMN1; SMN2HSD17B10 | |
| SCHEMBL7343198 | 0.77 | MAPK1 (0.39) | POLBALDH1A1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL29790092 | 0.73 | IKBKB (0.44) | POLBNR4A2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22902576 | 0.73 | IKBKB (0.44) | POLBNR4A2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29672030 | 0.73 | NR4A2 (0.46) | POLBNR4A2ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |