Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679804 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP1A2GLP1RADORA3ADORA2A | |
| SCHEMBL31353487 | 0.84 | GLP1R (0.48) | ALDH1A1GLP1RSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL17824419 | 0.83 | SMN1; SMN2 (0.43) | ALDH1A1CYP1A2SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL31353440 | 0.83 | KDM4E (0.40) | ALDH1A1CYP1A2GLP1RADORA3ADORA2A | |
| SCHEMBL15873205 | 0.78 | TSHR (0.42) | ALDH1A1CYP1A2GLP1RADORA3ADORA2A | |
| SCHEMBL27402005 | 0.77 | MAPT (0.47) | ALDH1A1CYP1A2GLP1RSMN1; SMN2KDM4E | |
| SCHEMBL17372703 | 0.76 | GLP1R (0.48) | ALDH1A1CYP1A2GLP1RADORA3ADORA2A | |
| SCHEMBL27402006 | 0.75 | KDM4E (0.45) | ALDH1A1CYP1A2GLP1RSMN1; SMN2KDM4E | |
| SCHEMBL31353496 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GLP1RSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL31183988 | 0.75 | GLP1R (0.40) | ALDH1A1CYP1A2GLP1RSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |