Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401711 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27402005 | 0.76 | MAPT (0.47) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31353337 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL32679804 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30905489 | 0.75 | GABRG2 (0.42) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27401986 | 0.75 | GABRG2 (0.42) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27401200 | 0.73 | BRD4 (0.45) | KDM4EALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL30905515 | 0.73 | BRD4 (0.45) | KDM4EALDH1A1RAB9ANPC1TP53 | |
| SCHEMBL2411055 | 0.72 | TSHR (0.48) | KDM4EALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL2405581 | 0.72 | TSHR (0.48) | KDM4EALDH1A1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |