Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14681047 | 0.98 | MEN1 (0.45) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL22953510 | 0.92 | MEN1 (0.50) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL22953516 | 0.92 | MEN1 (0.50) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL22953108 | 0.90 | MEN1 (0.52) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL22953107 | 0.90 | MEN1 (0.52) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL22953508 | 0.90 | MEN1 (0.52) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL12905322 | 0.89 | MEN1 (0.43) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL14681038 | 0.89 | CYP1A2 (0.43) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL3364608 | 0.88 | MEN1 (0.46) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL918125 | 0.88 | MEN1 (0.38) | MEN1KMT2ATP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025019953-A1 | ALTERNATING DUAL-ELECTROLYSER SYSTEMS AND METHODS FOR DIRECT AIR CAPTURE (DAC) AND RELEASE OF CO2 | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2025-01-30 | — | — | WO | disclosed |