SCHEMBL313550

SCHEMBL313550

CC(=O)OC(C(C)=O)(C(C)=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 8/20 0.60
▸ ADORA2B P29275 4/20 0.59
▸ HSP90B1 P14625 3/20 0.59
▸ ADORA2A P29274 3/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ TMEM97 Q5BJF2 1/20 0.59
▸ SIGMAR1 Q99720 1/20 0.59
▸ ADORA3 P0DMS8 5/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ ADORA1 P30542 2/20 0.58
▸ TSHR P16473 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ THRB P10828 1/20 0.58
▸ BLM P54132 1/20 0.58
▸ HSP90AA1 P07900 1/20 0.58
▸ DPP4 P27487 1/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ SLC28A1 O00337 1/20 0.57
▸ MAP3K7 O43318 1/20 0.57
▸ SLC28A2 O43868 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720980 0.89 AHCY (0.46) AHCYADORA2BHSP90B1ADORA2AHIF1A
SCHEMBL1120568 0.81 HINT1 (0.59) —
SCHEMBL15012908 0.80 PRMT5 (0.66) AHCYADORA2BHSP90B1ADORA2AHIF1A
SCHEMBL29913822 0.80 PRMT5 (0.69) AHCYADORA2BHSP90B1ADORA2AHIF1A
SCHEMBL5481897 0.80 AHCY (0.57) AHCYADORA2BHSP90B1ADORA2AHIF1A
SCHEMBL12987537 0.80 AHCY (0.63) AHCYADORA2BHSP90B1ADORA2AHIF1A
SCHEMBL11584743 0.79 P2RY1 (0.71) ADORA2BADORA2AADORA3KMT2AADORA1
SCHEMBL219554 0.79 P2RY1 (0.71) ADORA2BADORA2AADORA3KMT2AADORA1
SCHEMBL31001632 0.79 P2RY1 (0.71) ADORA2BADORA2AADORA3KMT2AADORA1
SCHEMBL5550634 0.79 P2RY1 (0.71) ADORA2BADORA2AADORA3KMT2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649222-B2 Compounds UNIVERSITETET I OSLO (NO) 2023-05-16 — — US disclosed
EP-3978488-A1 ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION Universitetet I Oslo (NO) 2022-04-06 — — EP disclosed
CN-109952297-B Compound (I) 奥斯陆大学 2022-02-25 — — CN disclosed
US-20210221791-A1 COMPOUNDS UNIVERSITETET I OSLO (NO) 2021-07-22 — — US disclosed
EP-3497095-B1 ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION UNIV OSLO (NO) 2021-07-14 — — EP disclosed
US-10961223-B2 Compounds UNIVERSITETET I OSLO (NO) 2021-03-30 — — US disclosed
US-20190284167-A1 COMPOUNDS UNIVERSITETET I OSLO (NO) 2019-09-19 — — US disclosed
EP-3497095-A1 COMPOUNDS Universitetet I Oslo (NO) 2019-06-19 — — EP disclosed
WO-2018033719-A1 COMPOUNDS UNIVERSITETET I OSLO (NO) 2018-02-22 — — WO disclosed
US-9374955-B2 Compositions and methods for anti-transpiration in plants INNOVATION HAMMER, LLC (US) 2016-06-28 — — US disclosed
US-9277697-B2 Compositions and methods for anti-transpiration in plants INNOVATION HAMMER, LLC (US) 2016-03-08 — — US disclosed
US-20150250171-A1 Compositions And Methods For Anti-Transpiration In Plants INNOVATION HAMMER LLC (US) 2015-09-10 — — US disclosed
US-20150250117-A1 Compositions And Methods For Anti-Transpiration In Plants INNOVATION HAMMER LLC (US) 2015-09-10 — — US disclosed
US-9072304-B2 Compositions and methods for anti-transpiration in plants INNOVATION HAMMER, LLC (US) 2015-07-07 — — US disclosed
US-20120077679-A1 Compositions And Methods For Anti-Transpiration In Plants INNOVATION HAMMER, LLC 2012-03-29 — — US disclosed
US-8093182-B2 Compositions and methods for anti-transpiration in plants INNOVATION HAMMER, LLC 2012-01-10 — — US disclosed
EP-1827095-A2 COMPOSITIONS AND METHODS FOR ANTI-TRANSPIRATION IN PLANTS Nonomura, Arthur M. (US) 2007-09-05 — — EP disclosed
WO-2006071645-A2 COMPOSITIONS AND METHODS FOR ANTI-TRANSPIRATION IN PLANTS NONOMURA ARTHUR M (US) 2006-07-06 — — WO disclosed
US-20060142158-A1 Compositions and methods for anti-transpiration in plants INNOVATION HAMMER, LLC 2006-06-29 — — US disclosed
US-6258749-B1 APPLYING WITH PHOTOCATALYST THE DOW CHEMICAL COMPANY 2001-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649222-B2 Compounds SLC30A6, SLC39A11, SLC39A3 AHCY 837/4885ADORA2B 2734/4885HSP90B1 2438/4885
US-10961223-B2 Compounds SLC30A6, SLC39A11, SLC30A5 AHCY 863/4885ADORA2B 2546/4885HSP90B1 2322/4885
US-20190284167-A1 COMPOUNDS SLC30A6, SLC39A11, SLC30A5 AHCY 863/4885ADORA2B 2546/4885HSP90B1 2322/4885
US-20210221791-A1 COMPOUNDS SLC30A6, SLC30A5, SLC39A11 AHCY 1782/4885ADORA2B 2997/4885HSP90B1 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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