Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | DLAT | P10515 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307809 | 0.87 | ALOX5 (0.78) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL817774 | 0.80 | ALOX5 (0.53) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL31576826 | 0.80 | ALOX5 (0.55) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL13629030 | 0.76 | ALOX5 (0.41) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL23195480 | 0.75 | ALOX5 (0.51) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL26444131 | 0.73 | ALOX5 (0.44) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL31576817 | 0.73 | ALOX5 (0.65) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL819795 | 0.71 | ALOX5 (0.71) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL12327984 | 0.71 | ALOX5 (0.71) | ALOX5XDHACHEKDM4EMEN1 | |
| SCHEMBL6275022 | 0.70 | ALOX5 (0.38) | ALOX5XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119326821-A | Nanoparticle loaded with hop beta-acid and 5-FU, and preparation method and application thereof | 宁夏医科大学总医院 | 2025-01-21 | — | — | CN | disclosed |