Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275024 | 1.00 | ALOX5 (0.38) | ALOX5FNTAFNTBXDHPTGS1 | |
| SCHEMBL6269718 | 0.83 | ALOX5 (0.44) | ALOX5FNTAFNTBPTGS1PPARG | |
| SCHEMBL6274814 | 0.83 | ALOX5 (0.44) | ALOX5FNTAFNTBPTGS1PPARG | |
| SCHEMBL6270487 | 0.79 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL6273624 | 0.77 | TRPV1 (0.42) | POLL | |
| SCHEMBL6273404 | 0.77 | TRPV1 (0.42) | POLL | |
| SCHEMBL21122607 | 0.74 | ALOX5 (0.45) | ALOX5TDP1 | |
| SCHEMBL6275233 | 0.72 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL31355460 | 0.70 | ALOX5 (0.61) | ALOX5XDH | |
| SCHEMBL817774 | 0.67 | ALOX5 (0.53) | ALOX5XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994093-B1 | POLYHYDROXYPHENOL DERIVATIVES AND PREVENTIVE AND THERAPEUTIC AGENTS FOR BONE AND CARTILAGE DISEASES CONTAINING THE SAME | HOECHST MARION ROUSSEL LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6177474-B1 | AROMATIC COMPOUND CONTAINING KETONE AND HYDROXY GROUPS | HOECHST MARION ROUSSEL (FR) | 2001-01-23 | — | — | US | disclosed |
| EP-0994093-A1 | POLYHYDROXYPHENOL DERIVATIVES AND PREVENTIVE AND THERAPEUTIC AGENTS FOR BONE AND CARTILAGE DISEASES CONTAINING THE SAME | Hoechst Marion Roussel, Ltd. (JP) | 2000-04-19 | — | — | EP | disclosed |