Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141728 | 0.91 | FAAH (0.56) | FAAHCES1 | |
| SCHEMBL1471376 | 0.91 | FAAH (0.57) | FAAHCES1 | |
| SCHEMBL3145054 | 0.90 | FAAH (0.55) | FAAHCES1 | |
| SCHEMBL3143800 | 0.87 | FAAH (0.53) | FAAHCES1 | |
| SCHEMBL1471172 | 0.86 | FAAH (0.59) | FAAHCES1 | |
| SCHEMBL1471464 | 0.86 | FAAH (0.59) | FAAHCES1 | |
| SCHEMBL1472093 | 0.86 | FAAH (0.61) | FAAHCES1 | |
| SCHEMBL1471994 | 0.85 | FAAH (0.60) | FAAHCES1 | |
| SCHEMBL1471210 | 0.85 | FAAH (0.60) | FAAHCES1 | |
| SCHEMBL1470963 | 0.84 | FAAH (0.62) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268817-B2 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-03-25 | — | — | US | disclosed |
| EP-2068862-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008030532-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.