Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616007 | 0.85 | KDM4E (0.40) | TMPRSS4CFTRALDH1A1TAS2R14 | |
| SCHEMBL29810864 | 0.80 | CFTR (0.50) | CFTRSOS1ALDH1A1ALOX15GAA | |
| SCHEMBL24917967 | 0.80 | CFTR (0.50) | CFTRSOS1ALDH1A1ALOX15GAA | |
| SCHEMBL11623934 | 0.77 | EPRS1 (0.35) | TMPRSS4CFTRCES2LMNAGAA | |
| SCHEMBL16647249 | 0.75 | KDM4E (0.40) | TMPRSS4CFTRALDH1A1TAS2R14 | |
| SCHEMBL22164127 | 0.72 | CES2 (0.47) | TMPRSS4CFTRCES2ALDH1A1ALOX15 | |
| SCHEMBL11626984 | 0.71 | CYP3A4 (0.38) | TMPRSS4CFTRCES2ALDH1A1GAA | |
| SCHEMBL16529867 | 0.68 | KDM4E (0.44) | ALDH1A1GAA | |
| SCHEMBL11632983 | 0.68 | GSK3B (0.42) | TMPRSS4CFTRLMNATAS2R14 | |
| SCHEMBL29244555 | 0.68 | TMPRSS4 (0.35) | TMPRSS4CES2ACP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051242-A1 | RAS INHIBITOR | 泰励生物科技（上海）有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119591588-A | RAS inhibitors | 泰励生物科技（上海）有限公司 | 2025-03-11 | — | — | CN | disclosed |