SCHEMBL31355822

SCHEMBL31355822

O=C1CCC(c2coc3ccc(NC(=O)CCCCCCCN4CCCCC4)cc23)C(=O)N1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TERT O14746 8/20 0.44
HTR1D P28221 3/20 0.40
HTR1B P28222 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31485008 0.93 CA1 (0.44) TERTHTR1DHTR1B
SCHEMBL31356023 0.91 HTR1D (0.39) TERTHTR1DHTR1B
SCHEMBL31484982 0.91 HTR1D (0.39) TERTHTR1DHTR1B
SCHEMBL31485026 0.90 CASP3 (0.42) TERTHTR1DHTR1B
SCHEMBL31355996 0.86 SIGMAR1 (0.39)
SCHEMBL31355861 0.86 SIGMAR1 (0.39)
SCHEMBL31356009 0.86 SIGMAR1 (0.39)
SCHEMBL31485058 0.85 KMT2A (0.42) HTR1DHTR1B
SCHEMBL23119736 0.83 KDM4E (0.43)
SCHEMBL31356181 0.83 HDAC3 (0.41) TERTHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 WO claimed