Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355946 | 0.92 | DDB1 (0.42) | TRPV1DDB1CRBNGSPT1 | |
| SCHEMBL31356248 | 0.91 | TRPV1 (0.47) | TRPV1DDB1CRBN | |
| SCHEMBL31355929 | 0.88 | DDB1 (0.54) | TRPV1HPGDDDB1CRBN | |
| SCHEMBL31356173 | 0.85 | TNF (0.58) | HPGDDDB1CRBNGSPT1TNF | |
| SCHEMBL31356047 | 0.84 | TRPV1 (0.43) | TRPV1HPGDHTR2CMCHR1 | |
| SCHEMBL31355925 | 0.83 | ACKR3 (0.44) | TRPV1DDB1CRBNGSPT1MCHR1 | |
| SCHEMBL31356060 | 0.82 | CRBN (0.44) | DDB1CRBNGSPT1 | |
| SCHEMBL31356206 | 0.82 | DDB1 (0.61) | TRPV1DDB1CRBN | |
| SCHEMBL31356153 | 0.81 | TRPV1 (0.49) | TRPV1HPGDDDB1CRBNTNF | |
| SCHEMBL31356185 | 0.81 | CRBN (0.46) | TRPV1DDB1CRBNGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |