SCHEMBL31355946

SCHEMBL31355946

O=C1CCC(c2ccc(NC(=O)c3ccc(CN4CCC(F)(F)CC4)c(F)c3)cc2)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 5/20 0.42
▸ CRBN Q96SW2 5/20 0.42
▸ GSPT1 P15170 1/20 0.42
▸ TRPV1 Q8NER1 5/20 0.39
▸ ACKR3 P25106 2/20 0.38
▸ POLB P06746 2/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ KIT P10721 2/20 0.37
▸ GSK3B P49841 1/20 0.36
▸ DYRK1A Q13627 1/20 0.36
▸ XDH P47989 1/20 0.36
▸ NAMPT P43490 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355855 0.92 TRPV1 (0.47) DDB1CRBNGSPT1TRPV1
SCHEMBL31355925 0.91 ACKR3 (0.44) DDB1CRBNGSPT1TRPV1ACKR3
SCHEMBL31356185 0.89 CRBN (0.46) DDB1CRBNGSPT1TRPV1ACKR3
SCHEMBL31355898 0.86 DDB1 (0.50) DDB1CRBNGSPT1ACKR3
SCHEMBL31356038 0.85 TRPV1 (0.36) DDB1CRBNGSPT1TRPV1ACKR3
SCHEMBL31356248 0.83 TRPV1 (0.47) DDB1CRBNTRPV1ACKR3
SCHEMBL31355918 0.83 DDB1 (0.50) DDB1CRBNGSPT1TRPV1ACKR3
SCHEMBL31356101 0.83 AURKB (0.42) DDB1CRBNTRPV1ACKR3HDAC6
SCHEMBL31355881 0.82 CRBN (0.44) DDB1CRBNGSPT1POLB
SCHEMBL31355929 0.80 DDB1 (0.54) DDB1CRBNTRPV1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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