Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.44 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355881 | 0.92 | CRBN (0.44) | CRBNDDB1GSPT1CXCR3POLB | |
| SCHEMBL31355867 | 0.91 | DDB1 (0.49) | CRBNDDB1GSPT1KDM4ESMN1; SMN2 | |
| SCHEMBL31355906 | 0.87 | DDB1 (0.58) | CRBNDDB1KDM4ESMN1; SMN2 | |
| SCHEMBL31356148 | 0.86 | CRBN (0.55) | CRBNDDB1GSPT1POLBHRH3 | |
| SCHEMBL31355774 | 0.83 | DDB1 (0.39) | CRBNDDB1GSPT1KDM4ESMN1; SMN2 | |
| SCHEMBL31356109 | 0.83 | CRBN (0.46) | CRBNDDB1GSPT1CXCR3 | |
| SCHEMBL31355855 | 0.82 | TRPV1 (0.47) | CRBNDDB1GSPT1 | |
| SCHEMBL31356252 | 0.82 | DDB1 (0.44) | CRBNDDB1KDM4ESMN1; SMN2HRH3 | |
| SCHEMBL31356226 | 0.81 | DDB1 (0.66) | CRBNDDB1KDM4ESMN1; SMN2 | |
| SCHEMBL31355880 | 0.80 | CRBN (0.47) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768392-A | Aryl or heteroaryl substituted glutarimide derivatives and uses thereof | 标新生物医药科技(上海)有限公司 | 2025-04-04 | — | — | CN | claimed |
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |