SCHEMBL31355880

SCHEMBL31355880

O=C1CCC(Nc2ccc(NCc3ccc(CN4CCC(F)(F)CC4)c(F)c3)cc2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.47
▸ DDB1 Q16531 19/20 0.47
▸ IKZF3 Q9UKT9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355766 0.92 CRBN (0.54) CRBNDDB1IKZF3
SCHEMBL31355906 0.91 DDB1 (0.58) CRBNDDB1
SCHEMBL31355881 0.88 CRBN (0.44) CRBNDDB1IKZF3
SCHEMBL31356120 0.88 CRBN (0.54) CRBNDDB1IKZF3
SCHEMBL31356226 0.83 DDB1 (0.66) CRBNDDB1
SCHEMBL31356109 0.83 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL31356185 0.82 CRBN (0.46) CRBNDDB1
SCHEMBL31356168 0.82 DDB1 (0.43) CRBNDDB1
SCHEMBL31356243 0.81 CRBN (0.62) CRBNDDB1IKZF3
SCHEMBL31356060 0.80 CRBN (0.44) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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