SCHEMBL31355898

SCHEMBL31355898

O=C1CCC(c2ccc(NC(=O)c3ccc(CN4CCC(F)(F)CC4)cc3)cc2)C(=O)N1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 2/20 0.50
▸ CRBN Q96SW2 2/20 0.50
▸ GSPT1 P15170 1/20 0.49
▸ NPC1 O15118 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ HIF1A Q16665 7/20 0.46
▸ EPAS1 Q99814 7/20 0.46
▸ TNF P01375 2/20 0.46
▸ CYP2C9 P11712 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ ACKR3 P25106 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ NOD2 Q9HC29 1/20 0.43
▸ NOD1 Q9Y239 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356173 0.90 TNF (0.58) DDB1CRBNGSPT1NPC1RAB9A
SCHEMBL31355937 0.90 ACKR3 (0.51) DDB1CRBNGSPT1NPC1RAB9A
SCHEMBL31356230 0.88 DDB1 (0.50) DDB1CRBNGSPT1NPC1RAB9A
SCHEMBL31355946 0.86 DDB1 (0.42) DDB1CRBNGSPT1ACKR3
SCHEMBL31356091 0.84 CRBN (0.53) DDB1CRBNGSPT1HIF1AEPAS1
SCHEMBL31356061 0.83 ACKR3 (0.41) DDB1CRBNGSPT1NPC1RAB9A
SCHEMBL31356107 0.81 RAB9A (0.49) DDB1CRBNNPC1RAB9AHIF1A
SCHEMBL31356106 0.81 DDB1 (0.58) DDB1CRBNGSPT1RAB9AHIF1A
SCHEMBL31356176 0.80 DDB1 (0.54) DDB1CRBNGSPT1RAB9AHIF1A
SCHEMBL27039530 0.78 CRBN (0.68) DDB1CRBNGSPT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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