SCHEMBL31356182

SCHEMBL31356182

O=C1CCC(Nc2cccc(NCc3ccc(CN4CCCCC4)cc3)c2)C(=O)N1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 19/20 0.77
▸ CRBN Q96SW2 19/20 0.77
▸ HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356221 0.90 DDB1 (0.67) DDB1CRBNHRH3
SCHEMBL31356243 0.89 CRBN (0.62) DDB1CRBN
SCHEMBL31356226 0.88 DDB1 (0.66) DDB1CRBN
SCHEMBL21965407 0.87 DDB1 (1.00) DDB1CRBN
SCHEMBL21965758 0.85 DDB1 (0.75) DDB1CRBNHRH3
SCHEMBL31356191 0.85 DDB1 (0.58) DDB1CRBNHRH3
SCHEMBL31356043 0.85 DDB1 (0.72) DDB1CRBN
SCHEMBL21965757 0.84 DDB1 (0.73) DDB1CRBN
SCHEMBL31355909 0.80 CRBN (0.65) DDB1CRBN
SCHEMBL31356217 0.80 CRBN (0.65) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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