SCHEMBL31356191

SCHEMBL31356191

O=C1CCC(c2cccc(NCc3ccc(CN4CCCCC4)cc3)c2)C(=O)N1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 13/20 0.58
▸ CRBN Q96SW2 13/20 0.58
▸ HRH3 Q9Y5N1 3/20 0.45
▸ GSPT1 P15170 1/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.41
▸ CACNA1B Q00975 3/20 0.40
▸ LTA4H P09960 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355804 0.90 CRBN (0.55) DDB1CRBNGSPT1IKZF3
SCHEMBL31356148 0.89 CRBN (0.55) DDB1CRBNHRH3GSPT1
SCHEMBL31355867 0.88 DDB1 (0.49) DDB1CRBNHRH3GSPT1IKZF3
SCHEMBL31356182 0.85 DDB1 (0.77) DDB1CRBNHRH3
SCHEMBL31356176 0.84 DDB1 (0.54) DDB1CRBNGSPT1
SCHEMBL31355931 0.81 CRBN (0.49) DDB1CRBNHRH3
SCHEMBL31355940 0.81 CRBN (0.49) DDB1CRBNHRH3
SCHEMBL31355809 0.81 CRBN (0.49) DDB1CRBNHRH3
SCHEMBL31355813 0.79 DDB1 (0.46) DDB1CRBNGSPT1
SCHEMBL31356091 0.78 CRBN (0.53) DDB1CRBNHRH3GSPT1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
Send feedback