Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356087 | 1.00 | DDB1 (0.45) | DDB1CRBNSIGMAR1CHRNA7HRH3 | |
| SCHEMBL31355763 | 0.89 | DDB1 (0.47) | DDB1CRBNHRH3MAOAMAOB | |
| SCHEMBL31355941 | 0.89 | DDB1 (0.47) | DDB1CRBNHRH3MAOAMAOB | |
| SCHEMBL31355770 | 0.87 | DDB1 (0.46) | DDB1CRBNHTR1ADRD2HTR2A | |
| SCHEMBL31356194 | 0.87 | DDB1 (0.46) | DDB1CRBNHTR1ADRD2HTR2A | |
| SCHEMBL31356098 | 0.87 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL31485206 | 0.84 | CACNA1G (0.44) | DDB1CRBNHTR1AHTR7 | |
| SCHEMBL31355983 | 0.84 | CACNA1G (0.44) | DDB1CRBNHTR1AHTR7 | |
| SCHEMBL31355869 | 0.83 | DDB1 (0.41) | DDB1CRBNITGB3ITGA2B | |
| SCHEMBL31355775 | 0.80 | CRBN (0.49) | DDB1CRBNHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026422-A1 | ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2025-02-06 | — | — | WO | claimed |