SCHEMBL31355775

SCHEMBL31355775

O=C1CCN(c2ccc(NCc3ccc(CN4CCC(F)(F)CC4)cc3)cc2)C(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 8/20 0.49
▸ DDB1 Q16531 7/20 0.49
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ GAA P10253 1/20 0.45
▸ HIF1A Q16665 1/20 0.41
▸ EPAS1 Q99814 1/20 0.41
▸ POLB P06746 1/20 0.39
▸ IKZF3 Q9UKT9 1/20 0.37
▸ HRH3 Q9Y5N1 2/20 0.36
▸ ENPP2 Q13822 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ DYRK1A Q13627 1/20 0.36
▸ TNKS O95271 1/20 0.36
▸ PARP1 P09874 1/20 0.36
▸ TNKS2 Q9H2K2 1/20 0.36
▸ CXCR3 P49682 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356168 0.88 DDB1 (0.43) CRBNDDB1L3MBTL1GAAGSK3B
SCHEMBL31356137 0.87 DDB1 (0.52) CRBNDDB1L3MBTL1GAAHIF1A
SCHEMBL31355868 0.87 CRBN (0.50) CRBNDDB1L3MBTL1GAAIKZF3
SCHEMBL31356107 0.83 RAB9A (0.49) CRBNDDB1HIF1AEPAS1
SCHEMBL31356087 0.80 DDB1 (0.45) CRBNDDB1HRH3
SCHEMBL31356255 0.80 DDB1 (0.45) CRBNDDB1HRH3
SCHEMBL31356091 0.80 CRBN (0.53) CRBNDDB1L3MBTL1GAAHIF1A
SCHEMBL31356120 0.79 CRBN (0.54) CRBNDDB1IKZF3
SCHEMBL31356252 0.77 DDB1 (0.44) CRBNDDB1L3MBTL1GAAHRH3
SCHEMBL31356129 0.75 DDB1 (0.53) CRBNDDB1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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