Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356350 | 0.84 | F2R (0.36) | RAB9ASMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL31356354 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL31356346 | 0.71 | NOTUM (0.38) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL31356332 | 0.70 | GUSB (0.45) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31356422 | 0.70 | GUSB (0.45) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31356356 | 0.67 | RBP4 (0.42) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL2914663 | 0.65 | TSHR (0.31) | — | |
| SCHEMBL31356363 | 0.64 | SMN1; SMN2 (0.45) | SLC6A3RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL31356412 | 0.64 | SMN1; SMN2 (0.45) | SLC6A3RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL31356362 | 0.64 | SMN1; SMN2 (0.45) | SLC6A3RAB9ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025032536-A1 | 1,3-DIAZA-4-OXA-[3.3.1]-BICYCLIC DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES, PARTICULARLY FOR THE TREATMENT OF OBESITY, DIABETES AND/OR NEURODEGENERATIVE DISEASES | UNIVERSITÀ DI PISA (IT) | 2025-02-13 | — | — | WO | disclosed |