Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109947 | 1.00 | HDAC1 (0.48) | HDAC1HDAC6ALDH1A1STSEPHX2 | |
| SCHEMBL30597150 | 0.84 | HDAC1 (0.65) | HDAC1HDAC6NOTUMKDM4EMEN1 | |
| SCHEMBL26113493 | 0.84 | HDAC1 (0.65) | HDAC1HDAC6NOTUMKDM4EMEN1 | |
| SCHEMBL31620916 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6MMP1MMP9MAPT | |
| SCHEMBL31620872 | 0.78 | HDAC1 (0.62) | HDAC1HDAC6MMP1MMP9MAPT | |
| SCHEMBL26587823 | 0.75 | HDAC1 (0.48) | HDAC1HDAC6ALDH1A1LMNAMAPT | |
| SCHEMBL5389996 | 0.74 | NOTUM (0.68) | NOTUMLMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL14230676 | 0.74 | DRD2 (0.55) | ALDH1A1STSNOTUMMAPTSMN1; SMN2 | |
| SCHEMBL31620871 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL31620933 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365454-A | Discovery of covalent EGFR inhibitors through cysteine 775 | 丹娜-法伯癌症研究院 | 2025-01-24 | — | — | CN | disclosed |