SCHEMBL31357356

SCHEMBL31357356

C[C@@H](O)[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 3/20 0.36
▸ OPRD1 P41143 3/20 0.36
▸ BACE1 P56817 3/20 0.35
▸ MME P08473 4/20 0.35
▸ PDCD1LG2 Q9BQ51 1/20 0.34
▸ CD274 Q9NZQ7 1/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ KISS1R Q969F8 3/20 0.33
▸ PRMT1 Q99873 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590364 0.94 OPRM1 (0.39) OPRM1OPRD1BACE1OPRK1KISS1R
SCHEMBL31391114 0.94 SLC6A2 (0.36) OPRM1OPRD1BACE1MME
SCHEMBL30607295 0.92 OPRD1 (0.37) OPRM1OPRD1BACE1OPRK1KISS1R
SCHEMBL29980611 0.92 OPRM1 (0.36) OPRM1OPRD1BACE1MME
SCHEMBL30645271 0.92 PDCD1LG2 (0.38) OPRM1OPRD1BACE1MMEPDCD1LG2
SCHEMBL30974040 0.92 OPRM1 (0.42) OPRM1OPRD1MMEPDCD1LG2CD274
SCHEMBL30006221 0.91 MAGI3 (0.40) OPRM1OPRD1BACE1KISS1R
SCHEMBL30781161 0.90 MME (0.41) MME
SCHEMBL30781165 0.90 MME (0.41) MME
SCHEMBL29549787 0.90 MME (0.41) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541817-A2 NUCLEIC ACID MOLECULE ENCODING CAR AND VECTOR INCLUDING THE SAME, IMMUNE CELL COMPRISING CAR AND PHARMACEUTICAL COMPOSITION INCLUDING THE CELL, METHOD FOR IMPROVING CYTOTOXIC ACTIVITY, AND METHOD FOR PRODUCING IMMUNE CELL COMPRISING CAR Mie University (JP) 2025-04-23 — — EP disclosed
CN-119613563-A Nucleic acid molecule encoding CAR, carrier containing CAR, immune cell containing CAR, manufacturing method of immune cell, pharmaceutical composition containing CAR and method for improving cell injury activity 国立大学法人三重大学 2025-03-14 — — CN disclosed
US-20250084180-A1 NUCLEIC ACID MOLECULE ENCODING CAR AND VECTOR COMPRISING THE SAME, IMMUNE CELL INCLUDING CAR AND PHARMACEUTICAL COMPOSITION COMPRISING THE CELL, METHOD FOR IMPROVING CYTOTOXIC ACTIVITY, AND METHOD FOR PRODUCING IMMUNE CELL INCLUDING CAR MIE UNIVERSITY (JP) 2025-03-13 — — US disclosed
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