Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450800 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAATMHSD17B10GAA | |
| SCHEMBL9025654 | 0.75 | HCAR2 (0.40) | HCAR2SMN1; SMN2LMNAATMKDM4E | |
| SCHEMBL16846497 | 0.72 | DYRK1A (0.39) | HCAR2SMN1; SMN2LMNAHSD17B10GAA | |
| SCHEMBL22315310 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHSD17B10GAAMEN1 | |
| SCHEMBL20470813 | 0.69 | HCAR2 (0.40) | HCAR2SMN1; SMN2LMNAHSD17B10GAA | |
| Hydrochloric Acid SCHEMBL9125490 | 0.69 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAATMHSD17B10GAA | |
| SCHEMBL8514383 | 0.67 | MEN1 (0.42) | HCAR2LMNAGAAMEN1KMT2A | |
| SCHEMBL19787513 | 0.65 | HCAR2 (0.36) | HCAR2LMNAHTTTSHR | |
| SCHEMBL26977763 | 0.64 | CASP1 (0.33) | HCAR2ATMALDH1A1CYP2D6 | |
| SCHEMBL3770602 | 0.64 | TAAR1 (0.42) | SMN1; SMN2LMNAATMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421709-A | Indazole-containing macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2025-02-11 | — | — | CN | disclosed |