Paraquat

Paraquat

SCHEMBL3135897

C[n+]1ccc(-c2cc[n+](C)cc2)cc1.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.70
SLC22A1 O15245 1/20 0.70
SLC22A3 O75751 1/20 0.70
SLC6A4 P31645 1/20 0.70
PABPC1 P11940 1/20 0.54
APOBEC3A P31941 1/20 0.54
EIF4H Q15056 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
QDPR P09417 2/20 0.48
HDAC8 Q9BY41 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7577787 0.92 SLC22A2 (0.85) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL21652 0.87 SLC6A4 (0.77) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL4895671 0.87 SLC6A4 (0.77) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL9650240 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL22370108 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL11281521 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL8331549 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL8677067 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
SCHEMBL14596518 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1
Paraquat SCHEMBL21653 0.84 SLC6A4 (0.72) SLC22A2SLC22A1SLC22A3SLC6A4PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411930-B1 ISOXAZOLINE COMPOUNDS HAVING MIF ANTAGONIST ACTIVITY CYTOKINE PHARMASCIENCES INC (US) 2013-01-16 EP claimed
EP-1952194-B1 ELECTROCHROMIC SYSTEM ON A PLASTIC SUBSTRATE SAINT GOBAIN (FR) 2010-07-14 EP claimed
WO-2017061995-A1 ELECTOCHROMIC COMPOSITION AND ELECTROMIC DEVICE USING SAME IGLASS TECHNOLOGY LLC (US) 2017-04-13 WO disclosed
EP-1330678-B1 ELECTROCHROMIC WINDOWS AND METHOD OF MANUFACTURING THE SAME GENTEX CORP (US) 2015-09-23 EP disclosed
US-7525714-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2009-04-28 US disclosed
US-20070103763-A1 ELECTROCHROMIC WINDOWS AND METHOD OF MAKING THE SAME GENTEX CORPORATION 2007-05-10 US disclosed
US-7154657-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2006-12-26 US disclosed
US-20060077511-A1 Electrochromic windows and method of making the same POLL DAVID L 2006-04-13 US disclosed
US-6972888-B2 Electrochromic windows and method of making the same GENTEX CORPORATION (US) 2005-12-06 US disclosed
EP-1330678-A4 ELECTROCHROMIC WINDOWS AND METHOD OF MANUFACTURING THE SAME GENTEX CORP (US) 2005-09-07 EP disclosed
US-20050117193-A1 ELECTROCHROMIC WINDOWS AND METHOD OF MAKING THE SAME POLL DAVID L (US) 2005-06-02 US disclosed
EP-1105442-B1 ELECTROCHROMIC MEDIA WITH CONCENTRATION-ENHANCED STABILITY, PROCESS FOR THE PREPARATION THEREOF AND USE IN ELECTROCHROMIC DEVICES GENTEX CORP (US) 2003-07-09 EP disclosed
US-20020075552-A1 Electrochromic windows and method of making the same POLL DAVID L (US) 2002-06-20 US disclosed
US-6407847-B1 Electrochromic medium having a color stability GENTEX CORPORATION 2002-06-18 US disclosed
US-6353493-B1 Electrochromic media with concentration-enhanced stability, process for the preparation thereof and use in electrochromic devices GENTEX CORPORATION 2002-03-05 US disclosed
WO-2002008826-A1 ELECTROCHROMIC WINDOWS AND METHOD OF MANUFACTURING THE SAME GENTEX CORPORATION (US) 2002-01-31 WO disclosed
US-20020005977-A1 Electrode design for electrochromic devices GUARR THOMAS F (US) 2002-01-17 US disclosed
EP-1105442-A2 ELECTROCHROMIC MEDIA WITH CONCENTRATION-ENHANCED STABILITY, PROCESS FOR THE PREPARATION THEREOF AND USE IN ELECTROCHROMIC DEVICES Gentex Corporation (US) 2001-06-13 EP disclosed
WO-2000066679-A2 ELECTROCHROMIC MEDIA WITH CONCENTRATION-ENHANCED STABILITY, PROCESS FOR THE PREPARATION THEREOF AND USE IN ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2000-11-09 WO disclosed
US-6137620-A Electrochromic media with concentration-enhanced stability, process for the preparation thereof and use in electrochromic devices GENTEX CORPORATION (US) 2000-10-24 US disclosed