Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413100 | 1.00 | POLB (0.59) | POLBUSP2HTTCNR2RAB9A | |
| SCHEMBL23413329 | 0.83 | GAA (0.60) | RAB9AKMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30097611 | 0.83 | GAA (0.60) | RAB9AKMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL15575804 | 0.79 | POLB (0.79) | POLBUSP2HTTCNR2RAB9A | |
| SCHEMBL19382699 | 0.79 | HTT (0.60) | POLBUSP2HTTRAB9AKMT2A | |
| SCHEMBL23444620 | 0.79 | EGFR (0.47) | POLBUSP2HTTCNR2RAB9A | |
| SCHEMBL23413118 | 0.78 | RAB9A (0.57) | POLBRAB9AKMT2AMEN1MAPT | |
| SCHEMBL30097503 | 0.78 | RAB9A (0.57) | POLBRAB9AKMT2AMEN1MAPT | |
| SCHEMBL16396288 | 0.77 | SUCNR1 (0.55) | — | |
| SCHEMBL6072225 | 0.77 | GRM4 (0.65) | POLBCNR2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348959-B | Heteroaryl compounds and their therapeutic use in conditions associated with altered beta-glucocerebrosidase activity | GT增益治疗股份有限公司 | 2025-01-07 | — | — | CN | disclosed |