Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.55 |
| ▸ | AURKA | O14965 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26907188 | 0.76 | ALDH1A1 (0.52) | PARP1AURKAKDM4EMEN1LMNA | |
| Oxypurinol SCHEMBL2017937 | 0.75 | GDA (0.41) | PARP1KDM4EMEN1LMNABLM | |
| SCHEMBL3081936 | 0.73 | PARP1 (0.71) | PARP1AURKAKDM4EMEN1LMNA | |
| SCHEMBL2411554 | 0.72 | PARP1 (0.62) | PARP1AURKAMEN1KMT2AAURKB | |
| SCHEMBL6531057 | 0.71 | PARP1 (1.00) | PARP1AURKAKDM4EMEN1LMNA | |
| SCHEMBL6046876 | 0.70 | PARP1 (0.57) | PARP1KDM4EMEN1LMNABLM | |
| SCHEMBL30539933 | 0.67 | PARP1 (0.57) | PARP1KDM4EMEN1LMNABLM | |
| SCHEMBL14324145 | 0.67 | PARP1 (0.57) | PARP1KDM4EMEN1LMNABLM | |
| SCHEMBL17293 | 0.66 | PARP1 (1.00) | PARP1KDM4EMEN1LMNABLM | |
| SCHEMBL31326568 | 0.66 | PARP1 (1.00) | PARP1KDM4EMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654321-A | PI3K alpha inhibitors | 突触活化疗法股份有限公司 | 2025-03-18 | — | — | CN | disclosed |